Recent Publications

2016

  1. Colmer HE, Howcroft AW, Jackston TA. (2016)  Formation, characterization and O-O bond activation of a peroxomanganese (III) complex supported by a cross-clamped cyclam ligand.  Inorg Chem 55(5), 2055-69.  PubMed – in process
  2. Kuehl C, Zhang T, Kaminskas LM, Porter CJ, Davies NM, Forrest L, Berkland C.  (2016)  Hyaluronic acid molecular weight determines lung clearance and biodistribution after instillation.  Mol Pharm 13(6), 1904-14.  PubMed – in process
  3. Leto DF, Massie AA, Colmer HE, Jackson TA.  (2016)  X-band electron paramagnetic resonance comparison of mononuclear Mn(IV)-oxo and Mn(IV)-hydroxo complexes and quantum chemical investigation of Mn(IV) zero-field slplitting.  Inorg Chem 55(7), 3272-82. PubMed – in process
  4. McNiff ML, Haynes EP, Dixit N, Gao FP, Laurence JS.  (2016) Thioredoxin fusion construct enables high-yield production of soluble, active matrix metalloproteinase-8 (MMP-8) in Escherichia coli.  Proten Exp Purif 122, 64-71.  PubMed – in process
  5. Tucker JK, McNiff ML, Ulapane SB, Spencer P, Laurence JS, Berrie CL. (2016) Mechanistic investigations of matrix metalloproteinase-8 inhibition by metal abstraction peptide.  Biointerphases, 11(2):021006.  PMC4851627
  6. Wang X, Hinshaw KC, Macdonald SJ, Chandler JR. (2016) Draft Genome Sequence of Chromobacterium violaceum Strain CV017. Genome Announc, 4(2).  doi:10.1128/genomeA.00080-16.  PMC4777762.

2015

  1. Ambler BR, Peddi S, Altman RA.  (2015)  Ligand-controlled regioselective copper-catalyzed trifluoromethylation to generate (trifluoromethyl)allenes.  Org Lett 17(10), 2506-9.  PMC4433581
  2. Ambler BR, Zhu L, Altman RA.  (2015)  Copper-catalyzed synthesis of trifluoroethylarenes from benzylic bromodifluoroacetates.  J Org Chem 80(16), 8449-57.  PMC4546558
  3. Fehl C, Hirt EE, Li SW, Aube J.  (2015) Temperature dependence of turnover in a Sc(OTf)3-catalyzed intramolecular Schmidt reaction.  Tetrahedron Lett 56(23), 3137-40.  PMC4465195
  4. Jamshidi RJ, Jacobs BA, Sullivan LC, Chavera TA, Saylor RM, Prisinzano TE, Clarke WP, Berg KA.  (2015)  Functional selectivity of kappa opioid receptor agonists in peripheral sensory neurons.  J Pharmacol Exp Ther 355(2), 174-182.  PMC4613959
  5. Meinig JM, Fu L, Peterson BR.  (2015). Synthesis of fluorophores that target small molecules to the endoplasmic reticulum of living mammalian cells.  Angew Chem Int Ed Eng 54(33), 9696-9.  PMC4539238
  6. Meinig JM, Peterson BR.  (2015). Anticancer/antiviral agent Akt inhibitor-IV massively accumulates in mitochondria and potentially disrupts cellular bioenergetics.  ACS Chem Biol 10(2), 570-6.  PMC4340353
  7. Paranjape SR, Riley AP, Somoza AD, Oakley CE, Wang CC, Prisinzano TE, Oakley BR, Gamblin TC. (2015) Azaphilones inhibit tau aggregation and dissolve tau aggregates in vitro. ACS Chem. Neurosci., 6, 751-60.  PubMed – in process
  8. Sullivan BP, EL-Gendy N, Kuehl C, Berkland C.  (2015)  Pulmonary delivery of vancomycin dry powder aerosol to intubated rabbits.  Mol Pharm 12(8), 2665-74. PubMed – in process

2014

  1. Ambler BR, Peddi S, Altman RA.  (2014)  Copper-catalyzed decarboxylative tirfluoromethylation of propargyl bromodifluoroacetates.  Synthesis 46(14), 1938-46.  PMC4185158
  2. Colmer HE, Geiger RA, Leto DF, Wijeratne GB, Day VW, Jackson TA.  (2014)  Geometric and electronic structure of a peroxomanganese(III) complex supported by a scorpionate ligand.  Dalton Trans 43(48), 17949-63.  PMC4237624
  3. Kuehl C, El-Gendy N, Berkland C. (2014) Nanoclusters surface area allows nanoparticle dissolution with microparticle properties.  J Pharm Sci 103(6), 1787-98.  PubMed – in process
  4. Meneely KM, Luo Q, Riley AP, Taylor B, Roy A, Stein RL, Prisinzano TE, Lamb AL.  (2014)  Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism. Bioorg Med Chem22, 5961-69.  PMC4254016
  5. Qiao Y, Zhu L, Ambler BR, Altman RA. (2014)  Decarboxylative fluorination strategies for accessing medicinally-relevant products.  Curr Top Med Chem 14(7), 966-78.  PMC4131449
  6. Riley AP, Groer CE, Young D, Ewald AW, Kivell BM, Prisinzano TE. (2014) Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analogues. J. Med. Chem., 57, 10464-75.  PMC4281103
  7. Thati S, Kuehl C, Hartwell B, Sestak J, Siahaan T, Forrest ML, Berkland C.  (2014)  Routes of administration and does optimization of soluble antigen arrays in mice with experimental autoimmune encephalomyelitis.  J Pharm Sci 104(2), 714-21.  PMC4312227

2013

  1. Motiwala, H.; Fehl, C.; Li, S.-L.; Hirt, E.; Porubsky, P.; Aubé, J. (2013) Overcoming Product Inhibition in Catalysis of the Intramolecular Schmidt Reaction. J. Am. Chem. Soc., 135, 9000. 
  2. Zhou, L.; Lovell, K.M.; Frankowski, K J.; Slauson, S.R.; Phillips, A.M.; Streicher, J.M.; Stahl, E.; Schmid, C.L.; Hodder, P.; Madoux, F.; Cameron, M.D.; Prisinzano, T.E.; Aubé, J.; Bohn, L.M. (2013) Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors. J. Biol. Chem., 288, 36703–36716. 
  3. Caspers, M.J.; Williams, T.D.; Lovell, K.M.; Lozama, A.; Butelman, E.R.; Kreek, M.J.; Johnson, M.; Griffiths, R.; MacLean, K.; Prisinzano, T.E. (2013) LC-MS Quantification of Salvinorin A from Biological Fluids. Anal. Methods., 5, 7042–7048.
  4. Krause, M.E.; Glass, A.M.; Jackson, T.A. Laurence, J.S.  (2013) Embedding the Ni-SOD mimetic Ni-NCC within a polypeptide sequence alters specificity of the reaction pathway. Inorg. Chem., 52, 77–83. 
  5. Pathwardhan, C.; Fauq, A.; Peterson, L.; Miller, C.; Blagg, B.; Chadli, A. Gedunin (2013) Inactivates the Co-Chaperone p23 Causing Breast Cancer Cell Death by Apoptosis. J. Biol. Chem., 288, 7313–7325.
  6. Armendariz, K.P.; Dunn, R.C. (2013) Ganglioside influence on phospholipid films investigated with single molecule fluorescence measurements. J. Phys. Chem. B, 117, 7959–7966.
  7. Kim, D.C.; Armendariz, K.P.; Dunn, R.C. (2013) Integration of Microsphere Resonators with Bioassay Fluidics for Whispering Gallery Mode Imaging. Analyst, 138, 3189–3195..
  8. Huckabay, H.A.; Armendariz, K.P.; Newhart, W.H.; Wildgen, S.M.; Dunn, R.C.  (2013) Near-Field Scanning Optical Microscopy for High Resolution Membrane Studies. Methods in Molecular Biology, 950, 373–394.
  9. DeVore, M.S.; Gull, S.F.; Johnson, C.K. (2013) Reconstruction of calmodulin single-molecule FRET states, dye interactions, and CaMKII peptide binding by MultiNest and classic maximum entropy. Chemical Physics, 422, 238–245.
  10. Schroll, P.; Fehl, C.; Dankesreiter, S.; König, B. (2013) Photocatalytic Surface Patterning of Cellulose using Diazonium Salts and Visible Light. Org Biomol. Chem., 11, 6510.
  11. Riley, A.P.; Day, V.W.; Navarro, H.A.; Prisinzano, T.E. (2013) Palladium-Catalyzed Transformations of Salvinorin A, a Neoclerodane Diterpene from Salvia divinorum. Org. Lett., 15, 5936–5939. 
  12. Ambler, B.R.; Altman, R.A. (2013) Copper-Catalyzed Decarboxylative Trifluoromethylation of Allylic Bromodifluoroacetates. Org. Lett.,15, 5578–5581.

2012

  1. Meneely, K.M.; Lamb, A.L. (2012) Two structures of a thiazolinyl imine reductase from Yersinia enterocolitica provide insight into catalysis and binding to the nonribosomal peptide synthetase module of HMWP1. Biochemistry, 51, 9002–9013.
  2. Iwai, A.; Bourboulia, D.; Mollapour, M.; Jensen-Taubman, S.; Lee, S.; Donnelly, A.C.; Yoshida, S.; Miyajima, N.; Tsutsumi, S.; Smith, A.K.; Sun, D.; Wu, X.; Blagg, B.S.; Trepel, J.B.; Stetler-Stevenson, W.G.; Neckers, L. (2012) Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells. Cell Cycle, 11, 3649–3655.
  3. Lovell, K.M.; Vasiljevik, T.; Arraya, J. J.; Lozama, A.; Prevatt-Smith, K.M.; Day, V.W.; Dersch, C.M.; Rothman, R.B.; Butelman, E.R.; Kreek, M.J.; Prisinzano, T.E. (2012) Semisynthetic Neoclerodanes as Kappa Opioid Receptor Probes. Bioorg. Med. Chem., 20, 3100–3110.
  4. Butelman, E.R.; Caspers, M.; Lovell, K.M.; Kreek, M.J.; Prisinzano, T.E. (2012) Behavioral Effects and CNS Levels of the Broadly Available Agonist Hallucinogen Salvinorin A are Affected by P-glycoprotein Modulation In vivo. J. Pharmacol. Exp. Ther., 341, 802–808.
  5. Glass A.M.; Krause M.E.; Laurence J.S.; Jackson T.A. (2012) Controlling the chiral inversion reaction of the metallopeptide Ni-asparagine-cysteine-cysteine with dioxygen. Inorg. Chem., 51, 10055–10063. 
  6. Olucha, J.; Meneely, K.M.; and Lamb, A.L. (2012) Modification of residue 42 of the active site loop with a lysine-mimetic sidechain rescues isochorismate-pyruvate lyase activity in Pseudomonas aeruginosa PchB.  Biochemistry 51,7525–7532.
  7. Duerfeldt, A.; Peterson, L.; Maynard, J.; Shinogle, H.; Moore, D.; Gewirth, D.; Argon, Y.; Nicchitta, C.; Blagg, B. (2012) Development of a Grp94 Inhibitor. J. Am. Chem. Soc., 134, 9796–9804.
  8. Peterson, L.; Eskew, J.; Vielhauer, G.; Blagg, B. (2012) The hERG channel is dependent upon the Hsp90α isoform for maturation and trafficking. Mol. Pharm., 9, 1841–1846.
  9. Kusuma, B.; Zhang, L.;Sundstrom, T.; Peterson, L.; Dobrowsky, R.; Blagg, B. (2012) Synthesis and Evaluation of Novologues as C-Terminal Hsp90 Inhibitors with Cytoprotective Activity against Sensory Neuron Glucotoxicity. J. Med. Chem., 55, 5795–5812.
  10. Zhao, H.; Yan, B.; Peterson, L.; Blagg, B. (2012) 3-Arylcoumarin derivatives manifest anti-proliferative activity through Hsp90 inhibition. ACS Med. Chem. Lett., 3, 327–331.
  11. Armendariz, K.P.; Huckabay, H.A.; Livanec, P.W.; Dunn, R.C. (2012) Single Molecule Probes of Membrane Structure: Orientation of BODIPY Probes in DPPC as a Function of Probe Structure. Analyst 137, 1402–1408. 
  12. Deckert, K.; Budiardjo, S.J.; Brunner, L. C.; Lovell, S.; Karanicolas, J. (2012) Designing allosteric control into enzymes by chemical rescue of structure. J. Am. Chem. Soc., 134, 10055–10060
  13. DeVore, M.S.; Gull, S.F.; Johnson, C.K. (2012) Classic Maximum Entropy Recovery of the Average Joint Distribution of Apparent FRET Efficiency and Fluorescence Photons for Single-Molecule Burst Measurements. J. Phys. Chem. B, 116, 4006–4015.

2011

  1. Hanson, P. R.; Chegondi, R.; Nguyen, J.; Thomas, C. D.; Waetzig, J. D.; Whitehead, A. (2011) Total Synthesis of Dolabelide C: A Phosphate-Mediated Approach. J. Org. Chem. 76, 4358–4370.
  2. Olucha, J.; Meneely, K.M.; Chilton, A.S.; Lamb. A.L. (2011). Two structures of an N-hydroxylating flavoprotein monooxygenase: the ornithine hydroxylase from Pseudomonas aeruginosa. J. Biol. Chem., 286, 31789-31798. 
  3. Schneider, C. M.; Khownium, K.; Li, W.; Spletstoser, J. T.; Haack, T.; Georg, G. I. (2011) Synthesis of Oximidine II Via a Cu-mediated Reductive Ene-Yne Macrocyclization. Angew. Chem. Int. Ed., 50, 7855–7857. 
  4. Eskew, J.D.; Sadikot, T.; Morales, P.; Duren, A.; Dunwiddie, I.; Swink, M.; Zhang, X.; Hembruff, S.; Donnelly, A.; Rajewski, R. A.; Blagg, B.S.; Manjarrez, J.R.; Matts, R.L.; Holzbeierlein, J M.; Vielhauer, G.A. (2011) Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells. BMC Cancer, 11, 468.
  5. Samadi, A.K.; Zhang, X.; Mukerji, R.; Donnelly, A.C.; Blagg, B.S.; Cohen, M.S. (2011) A novel C-terminal HSP90 inhibitor KU135 induces apoptosis and cell cycle arrest in melanoma cells. Cancer Lett., 312, 158–167.
  6. Matts, R.L.; Brandt, G.E.; Lu, Y.; Dixit, A.; Mollapour, M.; Wang, S.; Donnelly, A.C.; Neckers, L.; Verkhivker, G.; Blagg, B.S. (2011) A systematic protocol for the characterization of Hsp90 modulators. Biochem. Med. Chem. Lett., 19, 684–692.
  7. Zhao, H; Donnelly, A.C.; Kusuma, B.R.; Brandt, G.E.L.; Brown, D.; Rajewski, R A.; Vielhauer, G.; Holzbeierlein, J.; Blagg, B.S. J. (2011) Engineering an antibiotic to fight cancer: Optimization of the novobiocin scaffold to produce anti-proliferative agents. J. Med. Chem., 54, 3839–3853.
  8. Prevatt-Smith, K.M.; Lovell, K.M.; Simpson, D.S.; Day, V.W.; Douglas, J.T.; Bosch, P.; Dersch, C.M.; Rothman, R.B.; Kivell, B.; Prisinzano, T.E. (2011) Potential Drug Abuse Therapies Derived from the Hallucinogenic Natural Product Salvinorin A. Med. Chem. Comm., 2, 1217–1222.
  9. Lovell, K.M.; Prevatt-Smith, K.M.; Lozama, A.; Prisinzano, T.E. (2011) Synthesis of Neoclerodane Diterpenes and Their Pharmacological Effects. Top. Curr. Chem. (Chemistry of Opioids, H. Nagase, Ed. Springer Inc: Tokyo, 299, 141 – 185.
  10. Goodell, J.R.; Poole, J.L.; Beeler, A.B.; Aubé J.; Porco, Jr. J.A. (2011) Synthesis and Reactivity of Bicyclo[3.2.1]octanoid-Derived Cyclopropanes. J. Org. Chem. 76, 9792–9800.
  11. Thompson, C.M.; Poole, J.L.; Cross, J.L.; Akritopoulou-Zanze, I.; Djuric, S.W.  (2011) Small Molecule Library Synthesis Using Segmented Flow. Molecules, 16, 9161–9177.
  12. Krause, M.E.; Glass, A.M.; Jackson, T.A.; Laurence, J.S. (2011) MAPping the Chiral Inversion and Structural Transformation of a Metal-Tripeptide Complex Having Ni-Superoxide Dismutase Activity. Inorg. Chem., 50, 2479–2487. 
  13. Olucha, J. and Lamb, A.L. (2011) Mechanistic and structural studies of the N-Hydroxylating flavoprotein monooxygenases. Bioorg. Chem., 39, 171–177.
  14. Olucha, J.; Ouellette, A.N.; Luo, Q.; and Lamb, A.L. (2011) pH Dependence of Catalysis by Pseudomonas aeruginosa Isochorismate-Pyruvate Lyase: Implications for Transition State Stabilization and the Role of Lysine 42. Biochemistry, 50, 7198–7207. 
  15. Matts, R.L.; Dixit, A.; Peterson, L.B.; Sun, L.; Voruganti, S.; Kalyanaraman, P.; Hartson, S. D.; and B. S. J. Blagg. (2011) Elucidation of the Hsp90 C-terminal inhibitor binding site. ACS Chem. Biol., 6, 800–807. 
  16. Reddy Kusuma, B.; Peterson, L.B.; Vielhauer, G.; Holzbeierlein, J.; and Blagg, B.S.J. (2011) Targeting the Hsp90 Dimer with Dimeric Inhibitors. J. Med. Chem., 54, 6234–6253. 
  17. Davenport, J.; Manjarrez, J.; Peterson, L.; Blagg, B.; Matts, R. (2011) Gambogic acid, a natural product inhibitor of Hsp90. J. Nat. Prod., 74, 1085–1092.
  18. Fenster, E.; Fehl, C.; Aubé, J. (2011) Use of a Tandem Prins/Friedel–Crafts Reaction in the Construction of the Indeno-Tetrahydropyridine Core of the Haouamine Alkaloids: Formal Synthesis of (-)-Haouamine A. Org. Lett., 13, 2614–2617.

2010

  1. Reiff, E.A.; Nair, S.K.; Henri, J.T.; Greiner, J.F.; Reddy, B.S.; Chakrasali, R.; David, S.; Chiu, T.-L.; Amin, E.A.; Himes, R.H.; VanderVelde, D.G.; Georg, G.I. (2010) Total Synthesis and Evaluation of C26-Hydroxyepothilone D Derivatives for Photoaffinity Labeling of Tubulin. J. Org. Chem., 75, 86–94.
  2. Dickenson, N.E.; Armendariz, K.P.; Huckabay, H.A.; Livanec, P.W.;  Dunn, R.C. (2010) Near-field scanning optical microscopy: a tool for nanometric exploration of biological membranes. Analytical and Bioanalytical Chem., 396, 31–43.
  3. Culpepper, M. A.; Scott, E.E.; Limburg, J. (2010) Crystal structure of prolyl 4-hydroxylase from Bacillus anthracis. Biochemistry, 49, 124–33. 
  4. Donnelly, A.C.; Zhao, H.; Kusuma, B.R.; Blagg, B.S. J. (2010) Cytotoxic sugar analogues of an optimized novobiocin scaffold. Med. Chem. Comm., 1, 165–170.
  5. Mollapour, M.; Tsutsumi, S.; Donnelly, A.C.; Beebe, K.; Tokita, M.J.; Lee, M.-J.; Lee, S.; Morra, G.; Bourboulia, D.; Scroggins, B.T.; Colombo, G.; Blagg, B.S.; Panaretou, B.; Stetler-Stevenson, W.G.; Trepel, J.B.; Piper, P.W.; Prodromou, C.; Pearl, L.H.; Neckers, L. (2010) Swe1/Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function. Mol. Cell, 37, 333–343.
  6. Matthews, S.B.; Vielhauer, G.A.; Manthe, C.A.; Chaguturu, V.K.; Szabla, K.; Matts, R.L.; Donnelly, A.C.; Blagg, B.S.; Holzbeierlein, J.M. (2010) Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells. Prostate, 70, 27–36.
  7. Drinkwater, N.; Vu, H.; Lovell, K.M.; Criscione, K.R.; Collins, B.M.; Prisinzano, T.E.; Poulsen, S.; McLeish, M.J.; Grunewald, G.L.; Martin, J.M. (2010) Fragment-Based Screening by X-Ray Crystallography, MS and Isothermal Titration Calorimetry to Identify PNMT (phenylethanolamine N-methyltransferase) Inhibitors. Biochem. J., 431, 51–61.
  8. Treece, J.L.; Goodell, J.R.; Vander Velde, D.; Porco, Jr. J.A.; Aubé, J. (2010) Reaction Discovery Using Microfluidic-Based Multidimensional Screening of Polycyclic Iminium Ethers. J. Org. Chem., 75, 2028–2038.
  9. Krause, M.E.; Glass, A.M.; Jackson, T.A.; Laurence, J.S. (2010) Novel Tripeptide Model of Nickel Superoxide Dismutase. Inorg. Chem., 49, 362–364. 
  10. Peterson, L. and Blagg, B. (2010) Click chemistry to probe Hsp90: Synthesis and evaluation of a series of triazole-containing novobiocin analogs. Bioorg. Med. Chem. Lett., 20, 3957–3960.
  11. Dickenson, N.E.; Armendariz, K.P.; Huckabay, H.A. Livanec, P.W.; and Dunn, R.C. (2010) Near-field scanning optical microscopy: a tool for nanometric exploration of biological membranes. Analytical and Bioanalytical Chem., 396, 31–43.
  12. Price, E.S.; DeVore, M.S.; Johnson, C.K. (2010) Detecting Intramolecular Dynamics and Multiple Forster Resonance Energy Transfer States by Fluorescence Correlation Spectroscopy. Journal of Physical Chemistry B, 114, (17), 5895–5902. ​
  13. Prevatt-Smith, K.M.; Prisinzano, T.E. (2010) New Therapeutic Potential for Psychoactive Natural Products.  Nat. Prod. Rep., 27, 23–31.

2009

  1. Hutt, O.E.; Inagaki, J.; Reddy, B.S.; Nair, S.K.; Reiff, E.A.; Henri, J.T.; Greiner, J.F.; VanderVelde, D.G.; Chiu, T.-L.; Amin, E.A.; Himes, R.H.; Georg, G.I. (2009) Total Synthesis and Evaluation of C22-(3-azidobenzoyloxy)methyl  Epothilone C for Photoaffinity Labeling of b-Tubulin. Bioorg. Med. Chem. Lett.,19, 3293–3296.
  2. Hueston J.L. Suprenant K.A. (2009) Loss of dystrophin and the microtubule-binding protein ELP-1 causes progressive paralysis and death of adult C. elegans. Dev. Dyn., 238, 1878–1886.
  3. Meneely K.M.; Barr E.; Bollinger J.M. Jr; Lamb A.L. (2009).  Kinetic mechanism of ornithine hydroxylase (PvdA) from Pseudomonas aeruginosa: substrate triggering of O2 addition but not flavin reduction. Biochemistry 48, 4371–4376.
  4. Alontaga, A.Y.; Rodriguez, J.C.; Schonbrunn, E.; Becker, A.; Funke, T.; Yukl, E.T.; Hayashi, T.; Stobaugh, J.; Moenne-Loccoz, P.; Rivera, M. (2009) Structural Characterization of the Hemophore HasAp from Pseudomonas aeruginosa: NMR Spectroscopy Reveals Protein-Protein Interactions between Holo-HasAp and Hemoglobin. Biochemistry, 48, 96–109.
  5. Shelton, S.N.; Shawgo, M.E.; Comer, S.B.; Lu, Y.; Donnelly, A.C.; Szabla, K.; Tanol, M.; Vielhauer, G.A.; Rajewski, R.A.; Matts, R.L.; Blagg, B.S.; Robertson, J.D. (2009) KU135, a novel novobiocin-derived C-terminal inhibitor of Hsp90, exerts potent antiproliferative effects in human leukemic cells. Mol. Pharmacol., 76, 1314–1322.
  6. Simpson, D.S.; Lovell, K.M.; Lozama, A.; Han, N.; Dersch, C.M.; Rothman, R.B.; Prisinzano, T.E. (2009) Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Exploration of the Role of Furan Ring. Org. Biomol. Chem., 7, 3748–3756.
  7. Lovell, K.M.; Simpson, D.S.; Cunningham, C.W.; Prisinzano, T.E.  (2009) Utilizing Nature as a Source of New Probes for Opioid Pharmacology.  Fut. Med. Chem., 1, 285 – 301.
  8. Luo, Q.; Olucha, J.; Lamb, A.L. (2009) Structure – function analyses of isochorismate-pyruvate lyase from Pseudomonas aeruginosa suggest differing catalytic mechanisms for the two pericyclic reactions of this bifunctional enzyme.  Biochemistry 48, 5239–5245.
  9. Peterson, L. and Blagg, B. (2009) To fold or not to fold: Modulation and consequences of Hsp90 inhibition. Future Med. Chem., 1, 267–283.
  10. Amolins, M.; Peterson, L.; Blagg, B. (2009) Synthesis and Evaluation of Electron Rich Curcumin Analogues. Bioorg. Med. Chem. Lett., 17, 360–367.

One of 34 U.S. public institutions in the prestigious Association of American Universities
44 nationally ranked graduate programs.
—U.S. News & World Report
Top 50 nationwide for size of library collection.
—ALA
23rd nationwide for service to veterans —"Best for Vets," Military Times
KU Today