Recent Publications


2023

  1. Shimwell C, Atkinson L Graham MR, Murdoch B (2023).  A first molecular characterization of the scorpion telson microbiota of Hadrurus arizonensis and Smeringurus mesaensis.  PLoS One, 2023 January 17, Journal.pone, 2023, eCollection 2023. 
  2. Gary, S.; Landry, M.; Bloom, S. Spectral and Electrochemical Properties of Common Photocatalysts in Water: A Compendium for Aqueous Photoredox Catalysis. Synlett, 2023,34, 1911-1914.
  3. Alhammad YM, Parthasarathy S, Ghimire R, Kerr CM, O'Connor JJ, Pfannenstiel JJ, Chanda D, Miller CA, Baumlin N, Salathe M, Unckless RL, Zuñiga S, Enjuanes L, More S, Channappanavar R, Fehr AR (2023). SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice. Proc Natl Acad Sci U S A. 2023 Aug 29;120(35). Epub 2023 Aug 22.
  4. Kerr CM, Parthasarathy S, Schwarting N, O'Connor JJ, Giri E, More S, Orozco RC, Fehr AR (2023).PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell and tissue specific manner.Journal of Virology. 2023 Jun 17:2023.
  5. Ferreira Santos, MS, Kurfman E, Zamuruyev K, Noell AC, Mora MF, Willis PA (2023). A voltage trade study for the design of capillary electrophoresis instruments for spaceflight. Electrophoresis. 2023 Jan;44(1-2):10-14. Epub 2022 Jun 3.
  6. Yusuf-Makagiansar H, Yakovleva TV, Weldele M, Mahadik R, Siahaan TJ (2023). Evaluation of LFA-1 Peptide-Methotrexate Conjugates in Modulating Endothelial Cell Inflammation and Cytokine Regulation.Medical Research Archives. 2023 Feb;11(2):3534.
  7. Dissanayake GC,  Ndi CN,  Markley JL, Martinez JBHanson PR (2023). Total Synthesis of Sanctolide A and Formal Synthesis of (2 S)-Sanctolide A. J Org Chem. 2023 Jan 20;88(2):805-817. Epub 2023 Jan 5.
  8. Abisado-Duque RG, Townsend KA, McKee BM, Woods K, Koirala P, Alexandra J HolderJ, Craddock VD, Cabeen M, Chandler JR (2023). An Amino Acid Substitution in Elongation Factor EF-G1A Alters the Antibiotic Susceptibility of Pseudomonas aeruginosa LasR-Null Mutants. J Bacteriol. 2023 Jun 27;205(6). Epub 2023 May 16.
  9. Wen J, Dash RC, Zaino AM,  Harrahill NJ, Calhoun JT, Dusek CO, Morel SR, Russolillo M, Hadden MK (2023). 8-Hydroxyquinoline derivatives suppress GLI1-mediated transcription through multiple mechanisms. Bioorg Chem. 2023Mar:132:106387. Epub 2023 Jan 21.

2022

  1. Aquino Nunez W, Combs B, Gamblin TC, Ackley, B (2022).  Age-dependent accumulation of tau aggregation in Caenorhabditis elegans. Front. Aging, 2022 August 19.
  2. Javed S, Ganguly A, Dissanayake GC, Hanson PR. (2022). An iterative phosphate tether mediated approach for the synthesis of complex polyol subunits. Org Lett. 24(1):16-21. Epub 2021.
  3. Elballa W, Schwinghamer K, Ebert E, and Siahaan TJ (2022). Peptides and Their Delivery to the Brain. Springer International Publishing, Springer Nature, New York, 2022.
  4. Gary S, Bloom S (2022).  Carbocycles: From-SS-to-CC-via a Late-Stage "Snip-and-Stitch"ACS Cent. Sci. 2022, 8, 11, 1537-1547.
  5. Boyd EA, Hopkins Leseberg JA, Cosner EL, Lionetti D, Henke WC, Day VW, Blakemore JD (2022).  Remote oxidative activation of a [Cp*Rh] monohydride.  Chemistry. 28(13). Epub 2022.
  6. Henke WC, Stiel JP, Day VW, Blakemore JD (2022). Evidence for charge delocalization in diazafluorene ligands supporting low-valent [Cp*Rh] complexes. Chemistry 28(9). Epub 2022. 
  7. Klompen AML, Sanders SM, Cartwright P (2022). Venom system variation and the division of labor in the colonial hydrozoan Hydractinia symbiolongicarpus. Toxicon X. 14:100113. eCollection 2022.  
  8. Mahadik R, Kiptoo P, Tolbert T, Siahaan T (2022).  Immune Modulation by Antigenic Peptides and Antigenic Peptide Conjugates for Treatment of Multiple SclerosisMed Res Arch 10(5): 10.18103. Epub 2022.
  9. Singh P, Denler MC, Mayfield JR, Jackson TA (2022). Differences in chemoselectivity in olefin oxidation by a series of non-porphyrin manganese(IV)-oxo complexes.  Dalton Trans. 2022 Mar 29.
  10. Thomas H, McCloskey E, & Rider V. (2022). Pregnancy preparation: redistribution of CCR7-positive cells in the rat uterus. Reproduction (Cambridge, England), 2022 Sep 23;164(4), 183–193.

2021

  1. Amrein JDimond Z, Reboullet J, Hotze E. (2021). Bacterial unknown project in the COVID-19 era: Transition from in-person lab experience to online environment. J Microbiol Biol Educ. 22(1):2415. eCollection 2021. 
  2. Henke WC, Kerr TA, Sheridan TR, Henling LM, Takase MK, Day VW, Gray HB, Blakemore JD (2021).  Synthesis, structural studies, and redox chemistry of bimetallic [Mn(CO)3] and [Re(CO)3] complexes.  Dalton Trans. 50(8):2746-2756. Epub 20211. 
  3. Voth LS, O'Connor JJ, Kerr CM, Doerger E, Schwarting N, Sperstad P, Johnson DK, Fehr AR (2021).  Unique mutations in the murine hepatitis virus macrodomain differentially attenuate virus replication, indicating multiple roles for the macrodomain in coronavirus republican.  J Virol. 95(15). Epub 2021.
  4. Voth LS, O'Connor JJ, Kerr CM, Doerger E, Schwarting N, Sperstad P, Johnson DK, Fehr AR (2021).  An MHV macrodomain mutant predicted to lack ADP-ribose binding activity is severely attenuated, indicating multiple roles for the macrodomain in coronavirus republication. bioRxiv. 2021. Preprint.PMID. 
  5. Muffett KM, Klompen AML, Collins AG, Lewis Ames C. (2021). Raising awareness of the severity of "Contactless Stings" by Cassiopea Jellyfish and kin.  Animals (Basel). 11(12):3357.  
  6. Americus B, Hams N, Klompen AML, Alama-Bermejo G, Lotan T, Bartholomew JL, Atkinson SD (2021). The cnidarian parasite Ceratonova shasta utilizes inherited and recruited venom-like compounds during infection.  PeerJ. 9:e12606. eCollection 2021.
  7. Klompen AML, Kayal E, Collins AG, Cartwright P. (2021). Phylogenetic and selection analysis of an expanded family of putatively pore-forming jellyfish toxins (Cnidaria: Medusozoa).  Genome Biol Evol. 13(6).

2020

  1. Apley KD, Griffin JD, Johnson SN, Berkland CJ, DeKosky BJ (2020). Tetrameric fluorescent antigen arrays for single-step identification of antigen-specific B Cells. J Vis Exp. 2020 Oct 20;(164).
  2. Adeshina Y, Deeds EJ, Karanicolas J (2020).  Machine learning classification can reduce false positives in structure-based virtual screening.  Proc Natl Acad Sci U S A 117(31):18477-18488.
  3. Sorrentino JP, Ambler BR, Altman RA (2020). Late-Stage Conversion of a Metabolically Labile Aryl Methyl Ether-Containing Natural Product to Fluoroalkyl Analogues.  J Org Chem. 85(8):5416-5427. 
  4. Henke WC, Hopkins JA, Anderson ML, Stiel JP, Day VW, Blakemore JD (2020). 4,5-Diazafluorene and 9,9'-Dimethyl-4,5-Diazafluorene as ligands supporting redox-active Mn and Ru complexes. Molecules 25(14) 3189.
  5. Henke WC, Otolski CJ, Moore WNG, Elles CG, Blakemore JD (2020).  Ultrafast spectroscopy of [Mn(CO)3] complexes: tuning the kinetics of light-driven CO release and solvent binding.  Inorg Chem. 59(4) 2178-2187. Epub 2020  
  6. Christopher MA, Johnson SN, Griffin JD, Berkland CJ.  Autoantigen tetramer silences autoreactive B Cell populations. (2020).  Mol Pharm. 7(11):4201-4211. Epub 2020 Oct 6.
  7. Fehr AR, Singh SA, Kerr CM, Mukai S, Higashi H, Aikawa M (2020). The impact of PARPs and ADP-ribosylation on inflammation and host-pathogen interactions.Genes Dev. 34(5-6):341-359.
  8. Klompen AML, Macrander J, Reitzel AM, Stampar SN (2020).  Transcriptomic Analysis of Four Cerianthid (Cnidaria, Ceriantharia) Venoms.  Mar Drugs. 18(8):413.
  9. Ames CL, Klompen AML, Badhiwala K, Muffett K, Reft AJ, Kumar M, Janssen JD, Schultzhaus JN, Field LD, Muroski ME, Bezio N, Robinson JT, Leary DH, Cartwright P, Collins AG, Vora GJ (2020).  Cassiosomes are stinging-cell structures in the mucus of the upside-down jellyfish Cassiopea xamachana.  Commun Biol. 3(1):67.  
  10. Philip AT, Devkota S, Malvankar S, Bhattarai S, Meneely KM, Williams TD, Wolfe MS (2020).  Designed Helical Peptides as Functional Probes for γ-Secretase.  Biochemistry 5;58(44):4398-4407. Epub 2019 Oct 28.
  11. Mayfield JR, Grotemeyer EN, Jackson TA (2020).  Concerted proton-electron transfer reactions of manganese-hydroxyo and manganese-oxo complexes.  Chem Commun. (Camb). 56(65):9238-9255. Epub 2020
  12. Parham JD, Wijeratne GB, Mayfield JR, Jackson TA (2020).  Steric control of dioxygen activation pathways for MnII complexes supported by pentadentate, amide-containing ligands.  Dalton Trans. 48(34):13034-13045.
  13. Schilly KM, Gunawardhana SM, Wijesinghe MB, Lunte SM (2020).  Biological applications of microchip electrophoresis with amperometric detection: in vivo monitoring and cell analysisAnal Bioanal Chem. (24):6101-6119. Epub 2020 Apr 28.
  14. Soules KR, Dmitriev A, LaBrie SD, Dimond ZE, May BH, Johnson DK, Zhang Y, Battaile KP, Lovell S, Hefty PS (2020).  Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis support a role in TCA cycle regulationMol Microbiol 113, 68-88.
  15. Soules KR, LaBrie SD, May BH, Hefty PS (2020).  Sigma 54-Regulated transcription Is associated with membrane reorganization and Type III secretion effectors during conversion to infectious forms of Chlamydia trachomatis. mBio.11(5), e01725-20.

2019

  1. Denler MC, Massie AA, Singh R, Stewart-Jones E, Sinha A, Day VW, Nordlander E, Jackson TA (2019).  MnIV-Oxo complex of a bis(benzimidazolyl)-containing N5 ligand reveals different reactivity trends for MnIV-oxo than FeIV-oxo species.Dalton Trans. 48(15), 5007-5021.  
  2. de Azambuja F, Lovrien SM, Ross P, Ambler BR, Altman RA (2019). Catalytic One-Step Deoxytrifluoromethylation of Alcohols.  Org Chem. 15;84(4):2061-2071. 
  3. Benomar S,Evans KC, Unckless RL, Chandler JR (2019).  Efflux pumps in Chromobacterium species increase antibiotic resistance and promote survival in a coculture competitionmodel.  Appl Environ Microbiol 85(10), e00908-19.  
  4. Franklin M, Nepomnyachiy S, Feehan R, Ben-Tal N, Kolodny R, Slusky J (2019).  Efflux pumps represent possible evolutionary convergence onto the β-barrel fold.Structure 26(9), 1266-1274. 
  5. Boyd EA, Lionetti D, Henke WC​, Day VW, Blakemore JD (2019).  Preparation, characterization, and electrochemical activation of a model [Cp*Rh] hydride.Inorg. Chem.58, 3606-3615. 
  6. Lu R, Groer C, Kleindl PA, Moulder KR, Huang A, Hunt JR, Cai S, Aires DJ, Berkland CJ, Forrest ML (2019).  Formulation and preclinical evaluation of a Toll-like receptor 7/8 agonist as an anti-tumoral immunomodulator.J Controlled Release 306,165-176. 
  7. Robinson JL, Johnson PM, Kister K, Yin MT, Chen J, Wadhwa S (2019).  Estrogen signaling impacts temporomandibular joint and periodontal disease pathology. Odontology 108(2),153-165.
  8. Kenjic N, Hoag MR, Moraski G, Caperelli CA, Moran GR, Lamb AL (2019).PvdF of pyoveridin biosynthesis is a structuraly uniqu N10-formyltetrahydrofolate dependent formyltransferase.  Arch Biochem Biophys 664, 40-50.  
  9. Ames CL, Klompen AML, Badhiwala K, Muffett K, Reft A, Kumar M, Janssen JD, Field LD, Collins AG, Robinson JT, Cartright P, Vora GJ (2019).  Cassiosomes are stinging-cell structures in the mucus of the upside-down jellyfish Cassiopea xamachana.Commun Biol. 3(1), 67.  
  10. Leon MA, Fite RF, Ruffalo JK, Creusot RJ, Berkland C (2019).  Soluble antigen arrays displaying mimotopes direct the response of diabetogenic T cells.ACS Chem. Biol. 147, 1436-1448. 
  11. Griffin JD, Leon MA, Salash JR, Shao M, Hartwell BL, Pickens CJ, Sestak JO, Berkland C (2019).  Acute B-cell inhibition by soluble antigen arrays is valency-dependent and predicts immunomodulation in splenocytes.Biomacromolecules 20(5), 2115-2122. 
  12. Pickens CJ, Christopher MA, Leon MA, Pressnall MM, Johnson SN, Thati S, Sullivan BP, Berkland C (2019).  Antigen-drug conjugates as a novel therapeutic class for the treatment of antigen-specific autoimmune disorders.Mol. Pharmaceutics 16(6), 2452-2461.
  13. Leon MA, Wemlinger SM, Larson NR, Ruffalo JK, Sestak JO, Middaugh CR, Cambier JC, Berkland C (2019).  Soluble antigen arrays for selective desensitization of insulin-reactive B cells.Mol. Pharm. 16(4), 1563-1572. 
  14. Song JY, Larson NR, Thati S, Torres-Vazquez I,⁠ Martinez-Rivera N, Subelzu-Aispurua NJ, Leon MA, Rosa-Molinar E, Schoneich C, Forrest ML, Middaugh CR, Berkland CJ (2019).  Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation.J. Control. Release 293, 36-47.
  15.  Parham JD, Wijeratne GB, Mayfield JR, Jackson TA. (2019). Steric control of dioxygen activation pathways for MnII complexes supported by pentadentate, amide-containing ligands.  Dalton Trans. 48(34):13034-13045. Epub 2019.
  16. McFarlane JS, Hagen RA, Chilton AS, Forbes DL, Lamb AL, Ellis HR (2019).  Not as easy as π: An insertional residue does not explain the π-helix gain-of-function in two-component FMN reductases.Protein Sci. 28(1),123-134. 
  17. Ronnebaum TA, McFarlane JS, Prisinzano TE, Booker SJ, Lamb AL (2019).  Stuffed methyltransferase catalyzes the penultimate step of pyochelin biosynthesis.Biochemistry 58(6), 665-678. 
  18. McFarlane JS, Ronnebaum TA, Meneely KM, Chilton A, Fenton AW, Lamb AL (2019).  Changes in the allosteric site of human liver pyruvate kinase upon activator binding include the breakage of an intersubunit cation-π bond.Acta Crystallogr F Struct Biol Commun. 1;75(Pt 6), 461-469. 
  19. McFarlane, JS, Zhang J, Wang S, Lei X, Moran GR, Lamb AL (2019).  Staphylopine and pseudopaline dehydrogenase from bacterial pathogens catalyze reversible reactions and produce stereospecific metallophores.  J Biol Chem. 294(47),17988-18001. 
  20. Wang H, Ni HM, Chao X, Ma X, Rodriguez YA, Chavan H, Wang S, Krishnamurthy P, Dobrowsky R, Xu DX, Jaesche H, Ding WX (2019).  Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice.  Redox Biol. 101148
  21. de Azambuja F, Lovrien SM, Ross P, Ambler BR, Altman RA (2019).  Catalytic one-step deoxytrifluoromethylation of alcohols.J Org Chem. 84(4), 2061-2071. 
  22. Siegel JM, Schilly KM, Wijesinghe MB, Caruso G, Fresta CG, Lunte SM (2019).  Optimization of a microchip electrophoresis method with electrochemical detection for the determination of nitrite in macrophage cells as an indicator of nitric oxide production.  Anal. Methods 11, 148-156

2018

  1. Denler MC, Wijeratne GB, Rice DB, Colmer HE, Day VW, Jackson TA (2018).  MnIII-Peroxo adduct supported by a new tetradentate ligand shows acid-sensitive aldehyde deformylation reactivity.Dalton Trans. 47(38),13442-13458.  
  2. Ambler BR, Turnbull BWH, Suravarapu SR, Uteuliyev MM, Huynh NO, Krische MJ (2018).  Enantioselective Ruthenium-Catalyzed Benzocyclobutenone-Ketol Cycloaddition: Merging C-C Bond Activation and Transfer Hydrogenative Coupling for Type II Polyketide Construction.  J Am Chem Soc. 140(29):9091-9094. 
  3. Evans KC, Benomar S, Camuy-Velex LA, Nasseri EB, Wang X, Neuenswander B, Chandler JR (2018)  Quorum-sensing control of antibiotic resistance stabilizes cooperation in Chromobacterium violaceum. ISME J 12, 1263-1272.  
  4. Franklin M, Nepomnyachiy S, Feehan R, Ben-Tal N, Kolodny R, Slusky J (2018).  Evolutionary pathways of repeat protein topology in bacterial outer membrane proteins.eLife 7.
  5. Franklin MW, Slusky JSG (2018).  Tight turns of outer membrane proteins: An analysis of sequence, structure, and hydrogen bonding.J Mol Biol.430(18 Pt B), 3251-3265. 
  6. Mori-Quiroz LM, Hedrick SL, De Los Santos AR, Clift MD (2018).  A unified strategy for the syntheses of the isoquinolinium alkaloids berberine, coptisine, and jatrorrhizine.  Org. Lett. (14), 4281-4284. 
  7. Moore WNG, Henke WC, Lionetti D, Day VW, Blakemore JD (2018).  Single-electron redox chemistry on the [Cp*Rh] platform enabled by a nitrated bipyridyl ligand.  Molecules, 23(11)
  8. Pickens CJ, Johnson SN, Pressnall MM, Leon MA, Berkland, CJ (2018).  Practical considerations, challenges, and limitations of bioconjugation via azide-alkyne cycloaddition.  Bioconjugate Chemistry 29(3), 686-701. 
  9. Sherwood AM, Williamson SE, Johnson SN, Yilmaz A, Day VW, Prisinzano TE (2018).  Scalable regioselective and stereoselective synthesis of functionalized (E)-4-Iodobut-3-en-1-ols: gram-scale total synthesis of fungal decanolides and derivatives.The Journal of Organic Chemistry 83 (2), 980-992. 
  10. McAllister CT, Motriuk-Smith D, Kerr CM (2018).  Three new coccidians (cyclospora, eimeria) from eastern moles, scalopus aquaticus (linnaeus) (mammalia: soricomorpha: talpidae) from Arkansas, USA.Systematic Parasitology 95, 271. 
  11. Hartwell BL, Pickens CJ, Leon MA, Northrup, L, Christopher, MA, Griffin, JD, Martinez-Becerra F, Berkland C (2018).  Soluble antigen arrays disarm antigen-specific B cells to promote lasting immune tolerance in experimental autoimmune encephalomyelitis.J Autoimmun 93, 76-88.
  12. McFarlane JS, Davis CL, Lamb AL (2018).  Staphylopine, pseudopaline, and yersinopine dehydrogenases: A structural and kinetic analysis of a new functional class of opine dehydrogenase.J of Biological Chemistry 293, 8009-8019.
  13. Ronnebaum TA, Lamb AL (2018). Nonribosomal peptrides for iron axquisition: pyochelin biosynthesis as a case studyCurr Opin Structu Biol 52, 1-11. 

2017

  1. Massie AA, Denler MC, Cardoso LT, Walker AN, Hossain MK, Day VW, Nordlander E, Jackson TA (2017).  Equatorial ligand perturbations influence the reactivity of manganese(IV)-oxo complexes.Angew Chem Int Ed Engl. 56(15), 4178-4182. 
  2. Wurm T, Turnbull BWH, Ambler BR, Krische MJ (2017).  Thermal Hetero-Diels-Alder Reaction of Benzocyclobutenones with Isatins To Form 2-Oxindole Spirolactones. J Org Chem. 82(24):13751-13755. 
  3. Henke WC, Lionetti D, Moore WNG, Hopkins JA, Day VW, Blakemore, JD (2017).  Ligand substituents govern the efficiency and mechanistic path of hydrogen production with [Cp*Rh] catalysts.ChemSusChem10, 4589-4598.
  4. Hartwell BL, Pickens CJ, Leon MA, Berkland C (2017).  Multivalent soluble antigen arrays exhibit high avidity binding and modulation of B cell receptor-mediated signaling to drive efficacy against experimental autoimmune encephalomyelitis.Biomacromolecules18(6), 1893-1907. 
  5. McFarlane JS, Lamb AL (2017).  Biosynthesis of an opine metallophore by Pseudomonas aeruginosa.Biochemistry56(45), 5967-5971. 
  6. Sherwood AM, Williamson SE, Crowley RS, Abbott LM, Day VW, Prisinzano TE (2017).  Modular approach to pseudo-neoclerodanes as eesigner κ-opioid ligands.Org Lett. 19(19), 5414-5417. 

2016

  1. Colmer HE, Howcroft AW, Jackson TA (2016).  Formation, characterization, and O-O bond activation of a peroxomanganese(III) complex supported by a cross-clamped cyclam ligand.  Inorg Chem 55(5), 2055-69.   
  2. Ambler BR, Yang MH, Altman RA.Synlett (2016). Metal-catalyzed Decarboxylative Fluoroalkylation Reactions.  Synlett  (20):2747-2755. 
  3. Yang M, Hunt JR, Sharifi N, Altman RA (2016).  Palladium catalysis enables benzylation of α,α-difluoroketone enolates.  Angew Chem Int Ed Engl 55(31), 9080-9083
  4. Kuehl C, Zhang T, Kaminskas LM, Porter CJ, Davies NM, Forrest L, Berkland C (2016).  Hyaluronic acid molecular weight determines lung clearance and biodistribution after instillation.  Mol Pharm 13(6), 1904-14.  
  5. Leto DF, Massie AA, Colmer HE, Jackson TA (2016).  X-Band electron paramagnetic resonance comparison of mononuclear Mn(IV)-oxo and Mn(IV)-hydroxo complexes and quantum chemical investigation of Mn(IV) zero-field splitting.  Inorg Chem 55(7), 3272-82. 
  6. McNiff ML, Haynes EP, Dixit N, Gao FP, Laurence JS (2016).  Thioredoxin fusion construct enables high-yield production of soluble, active matrix metalloproteinase-8 (MMP-8) in Escherichia coli.  Protein Expr. Purif.122, 64-71.
  7. Tucker JK, McNiff ML, Ulapane SB, Spencer P, Laurence JS, Berrie CL (2016).  Mechanistic investigations of matrix metalloproteinase-8 inhibition by metal abstraction peptide.  Biointerphases 11(2), 021006. 
  8. Wang X, Hinshaw KC, Macdonald SJ, Chandler JR (2016).  Draft genome sequence of Chromobacterium violaceum strain CV017.Genome Announc, 4(2).  
  9. Ray JC, Wikersheim ML, Jalihal AP, Adeshina YO, Cooper TF, Balazsi G (2016).  Cellular growth arrest and persistence from enzyme saturation.PLoS Comput Biol. 12(3). 
  10. Sandhaus S, Annamalai T, Welmaker G, Houghten RA, Paz C, Garcia PK, Andres A, Narula G, Rodrigues FC, Geden S, Netherton M, Gupta R, Rohde KH, Giulianotti MA, Tse-Dinh Y-C (2016).  Small-molecule inhibitors targeting topoisomerase I as novel antituberculosis agents.Antimicrob Agents Chemother 60, 4028–4036.
  11. Meneely KM, Ronnebaum TA, Riley AP, Prisinzano TE, Lamb AL (2016). Holo Structure and Steady State Kinetics of the Thiazolinyl Imine Reductases for Siderophore Biosynthesis.  Biochemistry 55(38), 5423-33.

2015

  1. Ambler BR, Peddi S, Altman RA (2015).  Ligand-controlled regioselective copper-catalyzed trifluoromethylation to generate (trifluoromethyl)allenes.Org Lett 17(10), 2506-9.  
  2. Ambler BR, Zhu L, Altman RA (2015).  Copper-catalyzed synthesis of trifluoroethylarenes from benzylic bromodifluoroacetates.J Org Chem 80(16), 8449-57.  
  3. Fehl C, Hirt EE, Li SW, Aube J (2015).  Temperature dependence of turnover in a Sc(OTf)3-catalyzed intramolecular Schmidt reaction.Tetrahedron Lett 56(23), 3137-40.  
  4. Jamshidi RJ, Jacobs BA, Sullivan LC, Chavera TA, Saylor RM, Prisinzano TE, Clarke WP, Berg KA (2015).  Functional selectivity of kappa opioid receptor agonists in peripheral sensory neurons.J Pharmacol Exp Ther 355(2), 174-182.  
  5. Meinig JM, Fu L, Peterson BR (2015).  Synthesis of fluorophores that target small molecules to the endoplasmic reticulum of living mammalian cells.Angew Chem Int Ed Eng 54(33), 9696-9.  
  6. Meinig JM, Peterson BR (2015).  Anticancer/antiviral agent Akt inhibitor-IV massively accumulates in mitochondria and potently disrupts cellular bioenergetics.ACS Chem Biol 10(2), 570-6.  
  7. Paranjape SR, Riley AP, Somoza AD, Oakley CE, Wang CC, Prisinzano TE, Oakley BR, Gamblin TC (2015).  Azaphilones inhibit tau aggregation and dissolve tau aggregates in vitro.ACS Chem. Neurosci. 6(5),751-60. 
  8. Sullivan BP, EL-Gendy N, Kuehl C, Berkland C (2015).  Pulmonary delivery of Vancomycin dry powder aerosol to intubated rabbits.Mol Pharm12(8), 2665-74.

2014

  1. Ambler BR, Peddi S, Altman RA (2014).  Copper-catalyzed decarboxylative trifluoromethylation of propargyl bromodifluoroacetates.Synthesis 46(14), 1938-46. 
  2. Colmer HE, Geiger RA, Leto DF, Wijeratne GB, Day VW, Jackson TA (2014).  Geometric and electronic structure of a peroxomanganese(III) complex supported by a scorpionate ligand.Dalton Trans 43(48), 17949-63.  
  3. Kuehl C, El-Gendy N, Berkland C (2014).  NanoClusters surface area allows nanoparticle dissolution with microparticle properties.J Pharm Sci 103(6), 1787-98.   
  4. Meneely KM, Luo Q, Riley AP, Taylor B, Roy A, Stein RL, Prisinzano TE, Lamb AL (2014).  Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism.Bioorg Med Chem22, 5961-69.  
  5. Qiao Y, Zhu L, Ambler BR, Altman RA (2014).  Decarboxylative fluorination strategies for accessing medicinally- relevant products.Curr Top Med Chem 14(7), 966-78.  
  6. Riley AP, Groer CE, Young D, Ewald AW, Kivell BM, Prisinzano TE (2014).  Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analogues.J. Med. Chem., 57, 10464-75.  
  7. Thati S, Kuehl C, Hartwell B, Sestak J, Siahaan T, Forrest ML, Berkland C (2014).  Routes of administration and dose optimization of soluble antigen arrays in mice with experimental autoimmune encephalomyelitis.  J Pharm Sci 104(2), 714-21. 

2013

  1. Motiwala H, Fehl C, Li SL, Hirt E, Porubsky P, Aubé J (2013).  Overcoming product inhibition in catalysis of the intramolecular Schmidt reaction.J. Am. Chem. Soc., 135, 9000. 
  2. Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F, Cameron MD, Prisinzano TE, Aubé J, Bohn LM (2013).  Development of functionally selective, small molecule agonists at kappa opioid receptors.J. Biol. Chem. 288, 36703–36716. 
  3. Caspers MJ, Williams TD, Lovell KM, Lozama A, Butelman ER, Kreek MJ, Johnson M, Griffiths R, MacLean K, Prisinzano TE (2013).  LC-MS/MS quantification of salvinorin A from biological fluids.Anal. Methods 5, 7042–7048.
  4. Krause ME, Glass AM, Jackson TA, Laurence JS (2013).  Embedding the Ni-SOD mimetic Ni-NCC within a polypeptide sequence alters the specificity of the reaction pathway.Inorg. Chem., 52, 77–83. 
  5. Pathwardhan C, Fauq A, Peterson L, Miller C, Blagg B, Gedunin CA (2013).  Gedunin inactivates the co-chaperone p23 protein causing cancer cell death by apoptosis.J. Biol. Chem.288, 7313–7325.
  6. Armendariz KP; Dunn RC (2013).  Ganglioside influence on phospholipid films investigated with single molecule fluorescence measurements.J. Phys. Chem. B117, 7959–7966.
  7. Kim DC, Armendariz KP, Dunn RC (2013).  Integration of microsphere resonators with bioassay fluidics for whispering gallery mode imaging.Analyst, 138, 3189–3195.
  8. Huckabay HA, Armendariz KP, Newhart WH, Wildgen SM, Dunn RC (2013).  Near-field scanning optical microscopy for high-resolution membrane studies.Methods in Molecular Biology,950, 373–394.
  9. DeVore MS, Gull SF, Johnson CK (2013).  Reconstruction of calmodulin single-molecule FRET states, dye-interactions, and CaMKII peptide binding by MultiNest and classic maximum entropy.Chemical Physics422, 238–245.
  10. Schroll P, Fehl C, Dankesreiter S, König B (2013).  Photocatalytic surface patterning of cellulose using diazonium salts and visible light.Org Biomol. Chem.11, 6510.
  11. Riley AP, Day VW, Navarro HA, Prisinzano TE (2013).  Palladium-catalyzed transformations of salvinorin A, a neoclerodane diterpene from Salvia divinorum.Org. Lett. 15, 5936–5939. 
  12. Ambler BR, Altman RA (2013).  Copper-catalyzed decarboxylative trifluoromethylation of allylic bromodifluoroacetates.Org. Lett.15, 5578–5581.
  13. Schott JT, Mordaunt CE, Vargas AJ, Leon MA, Chen KH, Singh M, Cardenas EL, Maitra S, Patel NV, de Lijser HJ (2013).  Effects of structural and electronic characteristics of chalcones on the activation of peroxisome proliferator-activated receptor gamma.Chem Pharm Bull (Tokyo).61(2), 229-36

2012

  1. Meneely KM, Lamb AL (2012).  Two structures of a thiazolinyl imine reductase from Yersinia enterocolitica provide insight into catalysis and binding to the nonribosomal peptide synthetase module of HMWP1.Biochemistry51, 9002–9013.
  2. Iwai A, Bourboulia D, Mollapour M, Jensen-Taubman S, Lee S, Donnelly AC, Yoshida S, Miyajima N, Tsutsumi S, Smith AK, Sun D, Wu X, Blagg BS, Trepel JB, Stetler-Stevenson WG, Neckers L (2012).  Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells.Cell Cycle11, 3649–3655.
  3. Lovell KM, Vasiljevik T, Arraya JJ, Lozama A, Prevatt-Smith KM, Day VW, Dersch CM, Rothman RB, Butelman ER, Kreek MJ, Prisinzano TE (2012).  Semisynthetic neoclerodanes as kappa opioid receptor probes.Bioorg. Med. Chem.20, 3100–3110.
  4. Butelman ER, Caspers M, Lovell KM, Kreek MJ, Prisinzano TE (2012).  Behavioral effects and central nervous system levels of the broadly available κ-agonist hallucinogen salvinorin A are affected by P-glycoprotein modulation in vivo.J. Pharmacol. Exp. Ther.341, 802–808.
  5. Glass AM, Krause ME, Laurence JS, Jackson TA (2012).  Controlling the chiral inversion reaction of the metallopeptide Ni-asparagine-cysteine-cysteine with dioxygen.Inorg. Chem.51, 10055–10063. 
  6. Olucha J, Meneely KM, Lamb AL (2012).  Modification of residue 42 of the active site loop with a lysine-mimetic side chain rescues isochorismate-pyruvate lyase activity in Pseudomonas aeruginosa PchB.Biochemistry51, 7525–7532.
  7. Duerfeldt A, Peterson L, Maynard J, Shinogle H, Moore D, Gewirth D, Argon Y, Nicchitta C, Blagg B (2012).  Development of a Grp94 inhibitor.J. Am. Chem. Soc.134, 9796–9804.
  8. Peterson L, Eskew J, Vielhauer G, Blagg B (2012).  The hERG channel is dependent upon the Hsp90α isoform for maturation and trafficking.Mol. Pharm.9, 1841–1846.
  9. Kusuma B, Zhang L, Sundstrom T, Peterson L, Dobrowsky R, Blagg B (2012).  Synthesis and evaluation of novologues as C-terminal Hsp90 inhibitors with cytoprotective activity against sensory neuron glucotoxicity.J. Med. Chem.55, 5795–5812.
  10. Zhao H, Yan B, Peterson L, Blagg B (2012).  3-Arylcoumarin derivatives manifest anti-proliferative activity through Hsp90 inhibition.ACS Med. Chem. Lett.3, 327–331.
  11. Armendariz KP, Huckabay HA, Livanec PW, Dunn RC (2012).  Single molecule probes of membrane structure: orientation of BODIPY probes in DPPC as a function of probe structure.Analyst137, 1402–1408. 
  12. Deckert K, Budiardjo SJ, Brunner LC, Lovell S, Karanicolas J (2012).  Designing allosteric control into enzymes by chemical rescue of structure.J. Am. Chem. Soc.134, 10055–10060
  13. DeVore MS, Gull SF, Johnson CK (2012).  Classic maximum entropy recovery of the average joint distribution of apparent FRET efficiency and fluorescence photons for single-molecule burst measurements.J. Phys. Chem. B116, 4006–4015.
  14. Singh M, Schott JT, Leon MA, Granata RT, Dhah HK, Welles JA, Boyce MA, Oseni-Olalemi HS, Mordaunt CE, Vargas AJ, Patel NV, Maitra S (2012).  Design, synthesis and identification of a new class of triarylmethyl amine compounds as inhibitors of Apolipoprotein E production.Bioorganic Med. Chem. Lett. 22(19), 6252-6255.

2011

  1. Hanson PR, Chegondi R, Nguyen J, Thomas CD, Waetzig JD,Whitehead A (2011).  Total synthesis of dolabelide C: a phosphate-mediated approach.J. Org. Chem.76, 4358–4370.
  2. Olucha J, Meneely KM, Chilton AS, Lamb AL (2011).  Two structures of an N-hydroxylating flavoprotein monooxygenase: ornithine hydroxylase from Pseudomonas aeruginosa.J. Biol. Chem. 286, 31789-31798. 
  3. Schneider CM, Khownium K, Li W, Spletstoser JT, Haack T, Georg GI (2011).  Synthesis of oximidine II by a copper-mediated reductive ene-yne macrocyclization.Angew. Chem. Int. Ed.50, 7855–7857. 
  4. Eskew JD, Sadikot T, Morales P, Duren A, Dunwiddie I, Swink M, Zhang X, Hembruff S, Donnelly A, Rajewski RA, Blagg BS, Manjarrez JR, Matts RL, Holzbeierlein JM, Vielhauer GA (2011).  Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells.BMC Cancer11, 468.
  5. Samadi AK, Zhang X, Mukerji R, Donnelly AC, Blagg BS, Cohen MS (2011).  A novel C-terminal HSP90 inhibitor KU135 induces apoptosis and cell cycle arrest in melanoma cells.Cancer Lett. 312, 158–167.
  6. Matts RL, Brandt GE, Lu Y, Dixit A, Mollapour M, Wang S, Donnelly AC, Neckers L, Verkhivker G, Blagg BS (2011).  A systematic protocol for the characterization of Hsp90 modulators.Biochem. Med. Chem. Lett.19, 684–692.
  7. Zhao H, Donnelly AC, Kusuma BR, Brandt GEL, Brown D, Rajewski RA, Vielhauer G, Holzbeierlein J, Blagg BS (2011).  Engineering an antibiotic to fight cancer: optimization of the novobiocin scaffold to produce anti-proliferative agents.J. Med. Chem.54, 3839–3853.
  8. Prevatt-Smith KM,Lovell KM, Simpson DS, Day VW, Douglas JT, Bosch P, Dersch CM, Rothman RB, Kivell B, Prisinzano TE (2011).  Potential drug abuse therapeutics derived from the hallucinogenic natural product salvinorin A.Med. Chem.Comm.2, 1217–1222.
  9. Lovell KM, Prevatt-Smith KM, Lozama A, Prisinzano TE (2011).  Synthesis of neoclerodane diterpenes and their pharmacological effects.Top Curr Chem. 299, 141-85.
  10. Goodell JR, Poole JL, Beeler AB, Aubé J, Porco, Jr. JA (2011).  Synthesis and reactivity of bicyclo[3.2.1]octanoid-derived cyclopropanes.J. Org. Chem.76, 9792–9800.
  11. Thompson CM, Poole JL, Cross JL, Akritopoulou-Zanze I, Djuric SW (2011).  Small molecule library synthesis using segmented flow.Molecules 16, 9161–9177.
  12. Krause ME, Glass AM, Jackson TA, Laurence JS (2011).  MAPping the chiral inversion and structural transformation of a metal-tripeptide complex having ni-superoxide dismutase activity.Inorg. Chem.50, 2479–2487. 
  13. Olucha J, Lamb AL (2011).  Mechanistic and structural studies of the N-hydroxylating flavoprotein monooxygenases.Bioorg. Chem.39, 171–177.
  14. Olucha J, Ouellette AN, Luo Q, Lamb AL (2011).  pH Dependence of catalysis by Pseudomonas aeruginosa isochorismate-pyruvate lyase: implications for transition state stabilization and the role of lysine 42.Biochemistry50, 7198–7207. 
  15. Matts RL, Dixit A, Peterson LB, Sun L, Voruganti S, Kalyanaraman P, Hartson SD, Blagg BS (2011).  Elucidation of the Hsp90 C-terminal inhibitor binding site.ACS Chem. Biol. 6, 800–807. 
  16. Reddy Kusuma B, Peterson LB, Vielhauer G, Holzbeierlein J, Blagg BS (2011).  Targeting the heat shock protein 90 dimer with dimeric inhibitors.J. Med. Chem. 54, 6234–6253. 
  17. Davenport J, Manjarrez J, Peterson L, Blagg B, Matts R (2011).  Gambogic acid, a natural product inhibitor of Hsp90.J. Nat. Prod.74, 1085–1092.
  18. Fenster E, Fehl C, Aubé J (2011).  Use of a tandem Prins/Friedel-Crafts reaction in the construction of the Indeno-tetrahydropyridine core of the haouamine alkaloids: formal synthesis of (-)-haouamine A.Org. Lett.13, 2614–2617.

2010

  1. Reiff EA, Nair SK, Henri JT, Greiner JF, Reddy BS, Chakrasali R, David S, Chiu TL, Amin EA, Himes RH, VanderVelde DG, Georg GI (2010).  Total synthesis and evaluation of C26-hydroxyepothilone D derivatives for photoaffinity labeling of beta-tubulin.J. Org. Chem.75, 86–94.
  2. DickensonNE, Armendariz KP, Huckabay HA, Livanec PW,  Dunn RC (2010).  Near-field scanning optical microscopy: a tool for nanometric exploration of biological membranes.Analytical and Bioanalytical Chem. 396, 31–43.
  3. Culpepper MA, Scott EE, Limburg J (2010).  Crystal structure of prolyl 4-hydroxylase from Bacillus anthracis.Biochemistry49, 124–33. 
  4. Mollapour M, Tsutsumi S,Donnelly AC, Beebe K, Tokita MJ, Lee MJ, Lee S, Morra G, Bourboulia D, Scroggins BT, Colombo G, Blagg BS, Panaretou B, Stetler-Stevenson WG, Trepel JB, Piper PW, Prodromou C, Pearl LH, Neckers L (2010)Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function.Mol. Cell37, 333–343.
  5. Matthews SB, Vielhauer GA, Manthe CA, Chaguturu VK, Szabla K, Matts RL, Donnelly AC, Blagg BS, Holzbeierlein JM (2010).  Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells.Prostate70, 27–36.
  6. Drinkwater N, Vu H, Lovell KM, Criscione KR, Collins BM, Prisinzano TE, Poulsen S, McLeish MJ, Grunewald GL, Martin JM (2010).  Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors.Biochem. J.431, 51–61.
  7. Treece JL, Goodell JR, Vander Velde D, Porco, Jr. JA, Aubé J (2010).  Reaction discovery using microfluidic-based multidimensional screening of polycyclic iminium ethers.J. Org. Chem.75, 2028–2038.
  8. Krause ME, Glass AM, Jackson TA, Laurence JS (2010).  Novel tripeptide model of nickel superoxide dismutase.Inorg. Chem.49, 362–364. 
  9. Peterson L, Blagg B (2010).  Click chemistry to probe Hsp90: Synthesis and evaluation of a series of triazole-containing novobiocin analogues.Bioorg. Med. Chem. Lett. 20, 3957–3960.
  10. Dickenson NE, ArmendarizKP, Huckabay HA, Livanec PW, Dunn RC (2010).  Near-field scanning optical microscopy: a tool for nanometric exploration of biological membranes.Analytical and Bioanalytical Chem. 396, 31–43.
  11. Price ES, DeVore MS, Johnson CK (2010).  Detecting intramolecular dynamics and multiple Förster resonance energy transfer states by fluorescence correlation spectroscopy.Journal of Physical Chemistry B 114(17), 5895–5902. ​
  12. Prevatt-Smith KM, Prisinzano TE (2010).  New therapeutic potential for psychoactive natural products.Nat. Prod. Rep.27, 23–31.

2009

  1. Hutt OE, Inagaki J, Reddy BS, Nair SK, Reiff EA, Henri JT, Greiner JF, VanderVelde DG, Chiu TL, Amin EA, Himes RH, Georg GI (2009).  Total synthesis and evaluation of 22-(3-azidobenzoyloxy)methyl epothilone C for photoaffinity labeling of beta-tubulin.Bioorg. Med. Chem. Lett. 19, 3293–3296.
  2. Hueston JL, Suprenant KA (2009).  Loss of dystrophin and the microtubule-binding protein ELP-1 causes progressive paralysis and death of adult C. elegans.Dev. Dyn. 238, 1878–1886.
  3. Meneely KM, Barr E, Bollinger JM, Jr, Lamb AL (2009).  Kinetic mechanism of ornithine hydroxylase (PvdA) from Pseudomonas aeruginosa: substrate triggering of O2 addition but not flavin reduction.Biochemistry48, 4371–4376.
  4. Alontaga AY, Rodriguez JC, Schonbrunn E, Becker A, Funke T, Yukl ET, Hayashi T, Stobaugh J, Moenne-Loccoz P, Rivera M (2009).  Structural characterization of the hemophore HasAp from Pseudomonas aeruginosa: NMR spectroscopy reveals protein-protein interactions between Holo-HasAp and hemoglobin.Biochemistry 48, 96–109.
  5. Shelton SN, Shawgo ME, Comer SB, Lu Y, Donnelly AC, Szabla K, Tanol M, Vielhauer GA, Rajewski RA, Matts RL, Blagg BS, Robertson JD (2009).  KU135, a novel novobiocin-derived C-terminal inhibitor of the 90-kDa heat shock protein, exerts potent antiproliferative effects in human leukemic cells.Mol. Pharmacol.76, 1314–1322.
  6. Simpson DS, Lovell KM, Lozama A, Han N, Dersch CM, Rothman RB, Prisinzano TE (2009).  Synthetic studies of neoclerodane diterpenes from Salvia divinorum: role of the furan in affinity for opioid receptors.Org. Biomol. Chem.7, 3748–3756.​
  7. Lovell KM, Simpson DS, Cunningham CW, Prisinzano TE (2009).  Utilizing nature as a source of new probes for opioid pharmacology.Fut. Med. Chem. 1, 285 – 301.
  8. Luo Q, Olucha J, Lamb AL (2009).  Structure-function analyses of isochorismate-pyruvate lyase from Pseudomonas aeruginosa suggest differing catalytic mechanisms for the two pericyclic reactions of this bifunctional enzyme.Biochemistry 48, 5239–5245.
  9. Peterson L, Blagg B (2009).  To fold or not to fold: modulation and consequences of Hsp90 inhibition.Future Med. Chem.,1, 267–283.
  10. Amolins M, Peterson L, Blagg B (2009).  Synthesis and evaluation of electron-rich curcumin analogues.Bioorg. Med. Chem. Lett. 17, 360–367.